In situ formation of silver nanoparticles in thermosensitive glycogels and evaluation of its antibacterial activity

Shinde, vaishali S; kulkarni, anuja ; Dhanwe, Vaishali prakash; Dhumure, Archana Baburao; Khan, Aayesha ; Khanna, Pawan Kumar

Abstract

Copolymeric thermosensitive hydrogel, N-isopropylacrylamide and glycomonomer based on D-galactose have been synthesized by free radical polymerization using 2,2′-azobis-isobutyronitrile as initiator and ethylene glycol dimethacrylate as crosslinker. This hydrogel has been further used as template to synthesize AgNPs. The composite glycogel containing AgNPs has been characterized by different techniques and tested for antibacterial activity against E. coli and P. aeruginosa.


Keyword(s)

Nanomaterials, Silver nanoparticles, Hydrogels, Thermosensitive materials, Antibacterial activity, Free radical polymerization


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